RE:RE:RE:RE:RE:RE:RE:RE:RE:RE:PP speculation
A few add on comments (please correct me if anything I say is incorrect)
Ruvidar is the brand name for tld-1433, for the bladder
My understanding is that Rutherrin is the brand name for tld-1433 combined with transferrin.
Transferrin is a protein that floats around in blood and binds iron. It then presents itself to the outside of a cell. If the cell needs iron it expresses way more of something called transferrin receptor. Cancer cells have been show to have a lot of transferrin receptors as they are trying to grab any iron passing by. TLD-1433, contains ruthenium which is in the same column of the period table as iron. Same column means many similar properties. So transferrin protein seems to happily bind to tld-1433 and then when passing by, the cancer cell would grab it, assuming it is iron. Now it is in the cell. Trojan horsing it I guess.
I believe that the planned way to do this treatment is to premix the transferrin protein with the tld-1433 and then give it. That way already packaged and ready to go rather than depending on the tld-1433 wandering around looking for the patient's transferrin to bind to.
Eog can correct me but my understanding is Rutherrin is tld-1433 packaged together with transferrin to make the treatment drug.