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Destroying Cancer at the Speed of Light®

Clinical Study Underway (68 of 100 Patients Treated)
Expected to complete enrollment at the end of 2024
Expected to complete study at the end of 2026


Bullboard - Investor Discussion Forum Theralase Technologies Inc. V.TLT

Alternate Symbol(s):  V.TLT.WT | TLTFF

Theralase Technologies Inc. is a Canada-based clinical-stage pharmaceutical company. The Company is engaged in the research and development of light activated compounds and their associated drug formulations. The Company operates through two divisions: Anti-Cancer Therapy (ACT) and Cool Laser Therapy (CLT). The Anti-Cancer Therapy division develops patented, and patent pending drugs, called... see more

TSXV:TLT - Post Discussion

Theralase Technologies Inc. > Looking fwd to exciting Quarter Finally :-)
View:
Post by Oden6570 on Jan 02, 2024 5:50am

Looking fwd to exciting Quarter Finally :-)

Theralase® announced that it has successfully completed its non-Good Laboratory Practices ("GLP") preclinical toxicology analysis of Rutherrin® for Glio Blastoma Multiforme ("GBM"). GBM is the most aggressive and most common type of brain cancer.

The preclinical toxicology data collected to date has demonstrated that Theralase®'s Rutherrin® (RuvidarTM + human transferrin) PDC is able to be safely administered Intra Venously ("IV") into brain cancer animal models and then successfully hunt, target and significantly accumulate inside GBM cells versus healthy brain cells. When the PDC is activated by radiation therapy, such as X-ray radiation, it effectively destroys GBM tumour cells. In addition, to providing a strong cancer killing effect the technology is able to induce Immunogenic Cell Death ("ICD") and certain anti-tumour protective responses, preventing further growth of the GBM tumour cells.

Theralase® is forwarding a summary of the preclinical data to Health Canada for review and response on a GLP toxicology program to be completed by the Company by 1Q2024.

Based on the successful completion of the GLP toxicology program, Theralase® intends to commence a Phase Ia/Ib dose escalating clinical study in 2024 in patients diagnosed with GBM to determine the appropriate clinical dose of the drug from both a toxicity and tumour localization perspective. This phase will also look at radiation activation of a single IV dose of Rutherrin®.

Following the successful completion of the Phase Ia/Ib clinical study, Theralase® plans to commence a Phase IIa/IIb clinical study in Canada and the United States focused on enrolling and treating patients diagnosed with recurrent GBM, with multiple radiation activated doses of Rutherrin®

Theralase(R) Successfully Completes Non-GLP Toxicity Analysis for Brain Cancer (investorsobserver.com)

Comment by Oden6570 on Jan 02, 2024 5:55am
Dr. Arkady Mandel, MD, PhD, DSc, Chief Scientific Officer of Theralase® stated, "Theralase®'s scientific team has worked tirelessly to research and develop Rutherrin® as an IV PDC that post administration is able to be activated by radiation therapy to hunt, target and destroy GBM. The GLP toxicology program that Theralase® is completing will lay the groundwork for ...more  
Comment by StevenBirch on Jan 02, 2024 8:10am
The usual negative players say BTD won't move the stock much but it should because it is a big hurdle they will have cleared and more importantly what that will lead to. The obvious ones are AA and possible deals that can't or won't happen until then but also as Oden points out they are ready to move forward on GBM. And as Eog says the numbers support BTD being granted shortly so it ...more  
Comment by 99942Apophis on Jan 02, 2024 11:05am
Good points StevenBirch and also to note here is along with clearing those hurdles and with expectations of a well deserved price jump comes a landslide of investors exercising the August/2024 warrants to the tune of $20,000,000 into Theralase's coffers.  Personally I can't wait to convert my warrants into shares!
Comment by Yajne on Jan 02, 2024 12:00pm
....now that would be a welcome new thing here wouldn't it? ....warrants exercised and not simply extended GLTA patient longs here for a great 2024!!
Comment by patience69 on Jan 02, 2024 12:56pm
I'm not 100% sure but pretty sure that those warrants cannot be extended. They were 5 years already so that is it. They either get exercised or go bye bye
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The Road to Saving Lives: Clinical Study Underway

  • Clinical Study with 68 of 100 Patients Treated (Enrollment to be completed by end of 2024, with study completed by end of 2026)
     
  • Ground Floor Investment Opportunity in Multi-Billion Dollar Industry
     
  • Best-in-class treatment for NMIBC (according to interim clinical data)
     
  • NMIBC (Non-Muscle-Invasive Bladder Cancer)
     

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Contact Us

Address:
41 Hollinger Road
Toronto, ON M4B 3G4
Canada

Toll Free:
1-866-THE-LASE (843-5273)
Local Phone:
416-699-LASE (5273)

Email:
info@theralase.com

Fax:
416-699-5250