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Bullboard - Stock Discussion Forum ProMIS Neurosciences Inc PMN

Healthcare Biotechnology
ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational... see more

Bullboard (NDAQ:PMN)

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Post by BottomBrokeron Oct 30, 2024 9:40am

Well tolerated by cohort #5...

So we can put that one to rest. 
107
Discussion
Post by Gbathaton Oct 29, 2024 11:05pm

onward

https://www.investing.com/news/company-news/promis-shareholders-approve-key-stock-issuance-proposal-93CH-3681752 
94
Post by Gbathaton Oct 26, 2024 10:57pm

PMN oversold- Yahoo Finance

https://finance.yahoo.com/news/promis-neurosciences-inc-nasdaq-pmn-052948091.html
181
Comment by garygpon Oct 23, 2024 12:45pm

RE:AGM @ 10AM of Today EST

So G1945V, what you have posted pretty much ties in with what goldtech feels and posts frequently; no news, no known plans at least nothing was disclosed in this regard, no update on cohort #5 which ...more  
172
Discussion
Post by G1945Von Oct 23, 2024 11:44am

AGM @ 10AM of Today EST

It lasted no more than 10 minutes. No new information was provided, and there was no discussion at all. There was no new presentation.  I questioned the missing Cohort #5 of Phase 1. I did not ...more  
176
Discussion
Comment by Gbathaton Oct 20, 2024 9:05pm

RE:RE:RE:RE:RE:RE:Toxic soluble oligomers

safety data from Ph1a was not from AD patients Ph1b will be the first look at ARIA avoidance in vivo All previous data was in-vitro (lab bench showing no binding to plaque) Also, I think a bi ...more  
153
Discussion
Comment by Hafnesson Oct 20, 2024 4:14pm

RE:RE:RE:RE:RE:Toxic soluble oligomers

I thought it past the aria test with the safety data already released. 
78
Discussion
Comment by Gbathaton Oct 19, 2024 11:21pm

RE:RE:RE:RE:Toxic soluble oligomers

It definitely looks like a strong competitor in terms of the ALZ therapeutic market. If PMN310 can avoid ARIA as well, then I think it will still have a good chance of getting a good chunkc of the ...more  
94
Discussion
Comment by Speyeder999on Oct 17, 2024 10:13pm

RE:RE:RE:Toxic soluble oligomers

Thanks for clearing that up. Much appreciated !
102
Discussion
Comment by Gbathaton Oct 17, 2024 9:28pm

RE:RE:Toxic soluble oligomers

There is no comparison because it ALZ-801 is not an antibody.  It is a chemical that reduces formation of toxic oligomers and has been shown to reduce p-tau levels. They were supposed to finish ...more  
94
Discussion
Comment by Speyeder999on Oct 17, 2024 11:26am

RE:Toxic soluble oligomers

Unless i'm mistaken, i don't seem to recall seeing PMN310 compared to Alzheon's ALZ-801 in Promis's overviews or presentations. Is it because Alzheon is a private company?
78
Discussion
Post by goldtechon Oct 17, 2024 2:22am

Toxic soluble oligomers

large body of clinical and nonclinical evidence supports the role of neurotoxic soluble beta amyloid (amyloid, Aβ) oligomers as upstream pathogenic drivers of Alzheimer’s disease (AD). Recent late ...more  
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