How NOT to Run Clinical Trials 101.......
See Neurochem.......the Company that is The TextBook Example of How NOT to Run Clinical Trials 101.
Bellini's Neurochem had NO Pre-Clinical evidence of Efficacy related to the Mechanism of Action that could be acheived in Humans for their ( Spring 2007) FAILED DRUG 'Alzhemed' and carried the story right through Phaselll's. Steam Rolled it all the way juggling the Statistical Data and Omitting Efficacy related Drop-outs from the Data and Pizzing Off the FDA in the process.
Plain and Simple their FAILED DRUG ALZHEMED did NOT reach the Brain.........Never did.......Never will.
AZD-103 Does.....check it out.