Overview of the stockHere are some points to consider:
1) Biotech industry is very volatile though ISIS stock prices started accelerating upwards in August and have been smoothly trending up until December.
2) Positive quarterly earnings surprises.
3) Trading Volume has been quite low for the past 5 months - no particular good or bad news.
4) Success in the Biotech industry outweigh recessionary pressures as new patents posses high value in a medical market (which is a basic service)
Since in the past months the stock price has been falling, I suggest to keep watching the headlines for any new information. This company may have something big in store but could possibly just go down with the other