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Instil Bio Inc TIL

Instil Bio, Inc. is a clinical-stage biopharmaceutical company focused on developing a pipeline of novel therapies. The Company seeks to in-license/acquire and develop novel therapeutic candidates in diseases with significant unmet medical need. Its first such program is an engineered tumor infiltrating lymphocyte (TIL), cell therapy for the treatment of cancer. It is engaged in developing a novel class of genetically engineered TIL therapies using its Co-Stimulatory Antigen Receptor (CoStAR), platform. The Company's lead CoStAR-TIL product candidate, ITIL-306, expresses a CoStAR molecule designed to recognize folate receptor alpha (Fra), a tumor-associated antigen that is expressed on numerous solid tumors, including ovarian cancer, uterine cancer, NSCLC and renal cancer. CAR-T and TCR-T therapies are cell products composed of T cells that have been genetically engineered to recognize a specific cancer-related antigen on the surface of tumor cells.


NDAQ:TIL - Post by User

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Post by jim_nasium99on Sep 01, 2010 11:23am
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Post# 17404046

news!

news!
   

Golden Predator Corp (C-GPD) - News Release

Golden Predator signs option to double Yukon holdings

2010-09-01 10:08 ET - News Release
Shares issued 62,165,183
GPD Close 2010-08-31 C$ 0.51

Mr. William Sheriff reports

GOLDEN PREDATOR DOUBLES YUKON HOLDINGS

Golden Predator Corp. has signed an option agreement pursuant to which it can acquire a 100-per-cent interest in six separate properties located in east-central Yukon, which the company is calling the Rogue district. The property package comprises, in the aggregate, 3,154 quartz mineral claims covering approximately 659 km2 of land featuring Intrusion-Related Gold mineralization associated with several Tombstone Suite monzonitic intrusions.

"This acquisition doubles not only Golden Predator's land holdings but also the number of active projects we have in the Yukon. The potential of the Tintina trend and more particularly the Tombstone Gold Belt is just beginning to be realized on the heels of several significant recent discoveries," said William M. Sheriff, Chairman and CEO. "We are extremely excited to have this district-sized land package, which is immediately north of our Cynthia project, in our property portfolio. We look forward to conducting a number of geological studies on the entire area next year in preparation for a major drill campaign."

The Rogue district is located approximately 190 km northeast of Ross River, in east central Yukon. The project areas lie immediately north of the Company's Cynthia project, which is currently being drilled, within the eastern Tintina Gold Belt. The Tintina Gold Belt hosts several major deposits including Donlin Creek, Pogo, Fort Knox, Keno Hill, Dublin Gulch and Brewery Creek, as well as the recently discovered Rau, White Gold and Coffee deposits. The Rogue district is located approximately 20 km north of a winter road extending from the North Canol Road to the Plata Airstrip, and is accessible by helicopter and float plane.The Rogue district projects (referred to as Projects A through F) were staked to cover several Cretaceous Tombstone Suite monzonite intrusions, which intrude Proterozoic and Paleozoic metasediments of the Selwyn Basin, with associated Au-As soil anomalies and known Intrusion-Related Gold mineralization, Epithermal Gold-Silver Veins, and Porphyry Copper-Gold Deposits (Yukon Geological Survey Minfile 105O 009, 030, 039, 054, and 055). Historical grab samples of mineralized sheeted quartz veins up to 22.5 g/t have been reported in previous assessment reports.(1)

Mineralization and Geology

The Rogue district covers several mid-Cretaceous, granite to monzonite to granodiorite, Tombstone Plutonic Suite intrusions which intrude into late Proterozoic to Triassic marine sediments of the Selwyn Basin.Project A was staked to cover a 2.5 km wide, biotite granite to quartz monzonite intrusion called the Old Cabin Pluton, which intrudes into Upper Proterozoic to Ordovician sedimentary rocks consisting of shale, argillite, quartzite, chert and conglomerate with minor volcanoclastic rocks. The sedimentary rocks have been metamorphosed to a dark, fine-grained, magnetite hornfels with several skarn zones on the western edge of the pluton. Mineralization consists of sheeted quartz+calcite veins containing arsenopyrite, pyrite, and molybdenum. Union Carbide sampled these veins with the best result of 22.5 g/t (0.654 oz/t).(1)Project B was staked to cover several drainages with anomalous gold in stream sediment samples up to 192 ppb Au and 2,200 ppm As.(2) The Project area covers a sequence of upper Silurian to Devonian cherts, shales and argillites which have been intruded by a mid-Cretaceous granite to quartz-monzonitic stock. Mineralization and alteration are associated with the stock, the hornfels, and cross cutting veinlets.(3)

Project C was staked to cover a mid-Cretaceous, granitic to quartz monzonitic pluton which intrudes Devonian-Mississippian slates, argillites, and cherts. A 900 x 400 m zone of disseminated sulphide and arsenopyrite-quartz-tourmaline veins has been noted along the southeast flank of the intrusion. Mineralized veins range in thickness from 2 mm to 37.5 cm wide (average 3 cm) and return values ranging from 0.02 to 14 g/t Au.(4) The Company believes this may represent a classic sheeted vein zone target typical of deposits such as Dublin Gulch, Gold Dome and Clear Creek.Project D was staked to cover a 12 km by 2.5 km mid-Cretaceous granitic pluton, called the Emerald Lake Pluton, which intrudes Cambrian to Devonian meta-sedimentary rocks of the Selwyn Basin. Mineralization associated with the Emerald Lake Pluton consists of parallel sheeted, quartz veins ranging from 1 to 10 cm in width with variable gold with channel samples returning values up to 10 m of 5.6 g/t.(5)Project E was staked to cover the margin of a large mid-Cretaceous granitic to quartz monzonitic pluton called the Rogue Pluton. Mineralization is associated with quartz vein-stockwork system in the contact 1-2 km contact aureole around the pluton. Quartz veins extend about 20 to 30 m into the granite and outward about 110 to 200 m into the sedimentary rocks. They contain auriferous pyrrhotite and pyrite, and minor chalcopyrite, molybdenite, galena and sphalerite. Disseminated sulphides also occur, and are frequently concentrated along fold hinges. Mineralized areas are marked by extensive gossans with rock chip samples up to 6.56 g/t.(6)Project F was staked to cover a large northwest trending sequence of Ordovician to Silurian shales and cherts with 7 stream sediment samples with anomalous gold ranging from 15 ppb Au up to 100 ppb Au.(2)

Current Work

Golden Predator is currently compiling all historical geological data for the Rogue District, and will use this data to plan future work programs for this property leading to the establishment of drill targets in 2011.

Transaction Terms

The Company has acquired options (the "Options") on six separate claim blocks (the "Claim Blocks"), each comprised of between 446 and 586 quartz claims.

As consideration for the Options, the Company will pay to 18526 Yukon Inc. (Ron Berdahl) $25,000 and issue 250,000 common shares. In addition, the Company will reimburse 18526 Yukon Inc. for out-of-pocket staking costs incurred of approximately $490,000 and, following confirmation of registration of certain of the claims comprised in the Property, an additional sum of $330,880.

To exercise all of the Options, the Company will, in stages, pay and issue an additional $3,475,000 and 4,250,000 shares (3,650,000 of which are subject to a value cap of $7,100,000) by September, 2017 and incur exploration expenditures of $10,000,000 by December 31, 2015.Future cash and share obligations will be reduced by 14% for each Claim Block the Company drops.Each of the Claim Blocks will be subject to a 3% NSR in favor of 18526 Yukon Inc., and the Company has the right to repurchase 1% of the NSR on any particular Claim Block for $1,000,000. Of the $3,475,000 to be paid in cash, $2,175,000 is an advance royalty payment which will be deducted from any payments due under the NSRs.

In addition to the upfront cash and share payments, the Company has committed to paying an additional $50,000 in cash and issuing an additional 150,000 shares on the first anniversary of the agreement, as well as incurring $1,000,000 of exploration expenditures on the Property before December 31, 2011. All other payments, expenditures and issuances are optional.The agreement is subject to several conditions, including all required regulatory approvals.

We seek Safe Harbor.

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