for janitor1 & sprulethis board might feel more intelligent so don't abuse it... nan not this board no way, back to basic.
do not forget that Bioniche have more under its umbrella just check product on their website (NDA:free pump)
bladder preservation therapy for locally invasive bladder cancer:Combined therapy using balloon-occluded arterial infusion of anticanceragent and hemodialysis with concurrent radiation
Abstract. We investigated the effect of balloon-occluded arterial infusion (BOAI) of anticancer agent (cisplatin/gem- citabine), used concomitantly with hemodialysis, which delivers an extremely high concentration of anticancer agent to the site of a tumor without systemic adverse effects, along with concurrent radiation (referred to as the OMC-regimen) in patients with advanced bladder cancer. One hundred and ninety-two patients were assigned to receive either the OMC- regimen (n=96) or total cystectomy (n=96). Patients in the OMC-regimen group who failed to achieve CR underwent cystectomy, or secondary BOAI with an increased amount of CDDP or gemcitabine (1600 mg). The OMC-regimen allowed >89% (69/77) of patients with locally invasive tumors to achieve CR [>70% (70/96) of all patients including those with T4 and N(+) disease]. Most (68/69) of the CR patients were still alive with no evidence of recurrence after a mean follow-up of 161 (range 12-805) weeks. The 5- and 15-year overall survival rates were 91.5 and 81.3% (vs. 59.8% and 40.1% for cystectomy, P<0.0001), respectively.
https://www.bladdercancersupport.org/index.php?option=com_kunena&Itemid=114&func=view&catid=31&id=34095Novel