ProMIS Neurosciences Inc PMN

Healthcare Biotechnology

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.

NDAQ:PMN - Post by User

ProMIS Neurosciences Inc

Bullboard Posts

Post by Chainsawwon Nov 19, 2010 8:50pm

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Post# 17733046

BROKER SUMMARY NOV 19

House Positions for C:AMF from 20101119 to 20101119

House	Bought	$Val	Ave	Sold	$Val	Ave	Net	$Net
85 Scotia	163,500	76,295	0.467	25,500	12,097	0.474	138,000	-64,198
7 TD Sec	43,500	21,065	0.484	29,500	13,665	0.463	14,000	-7,400
19 Desjardins	34,966	16,113	0.461	22,166	10,511	0.474	12,800	-5,602
33 Canaccord	30,000	14,516	0.484	22,000	10,477	0.476	8,000	-4,039
79 CIBC	6,500	2,742	0.422	5,100	2,295	0.45	1,400	-447
99 Jitney	1,500	727	0.485	1,500	742	0.495	0	15
1 Anonymous	0			1,000	490	0.49	-1,000	490
2 RBC	0			4,000	1,810	0.453	-4,000	1,810
81 HSBC	0			35,200	17,242	0.49	-35,200	17,242
9 BMO Nesbitt	0			38,500	17,685	0.459	-38,500	17,685
124 Questrade	8,500	3,717	0.437	51,500	24,332	0.472	-43,000	20,615
80 National Bank	10,000	4,500	0.45	62,500	28,329	0.453	-52,500	23,829
TOTAL	298,466	139,675	0.468	298,466	139,675	0.468	0	0