GREY:IPHAF - Post by User
Post by
narcissiston Oct 05, 2011 10:28am
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Post# 19120734
NEWS: Voclosporin study published in the American
NEWS: Voclosporin study published in the American
Voclosporin study published in the American Journal of Transplantation
Conclusions:
"The AJT is the highest impact journal in the field of transplantation,and we are very pleased to have voclosporin featured in such aprestigious publication. Calcineurin inhibitors (currentlycyclosporine and TAC) remain the cornerstone of immunosuppressanttherapy for transplant patients. NODAT is an important concern withTAC. The literature demonstrates that NODAT results in increased graftloss by 3 years, a 23% increase in patient death at 5 years, with anannual cost of $12,0001,2,3. We anticipate that our novel calcineurin inhibitor, voclosporin, willprovide a significant benefit in this regard, as well as cause lessdiarrhea and tremors. Furthermore, the clear relationship betweenblood concentrations of voclosporin and clinical outcomes withvoclosporin is another distinct advantage as it should enhance ease ofdosing and monitoring for both physicians and patients," commented Dr.Robert Foster, CEO of Isotechnika.