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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Bullboard Posts
Comment by BearDownAZon Feb 20, 2013 2:55pm
200 Views
Post# 21018062

RE: RE: RE: A Little More Explanation

RE: RE: RE: A Little More Explanation

IMO, nothing is coming out between now and the ACC conference (2nd week of March) at which I suspect they will formally present the SUSTAIN trial. Remember, they've only released topline SUSTAIN data thus far. One potential scare from the ASSERT trial was the elevation in liver transaminases during this 12-week treatment period. DM and RVX have mentioned in their blogs/press releases that in the longer SUSTAIN trial that these transaminases came down. So when RVX formally presents this SUSTAIN data, this will alleviate a lot of concerns for the safety of this drug.

So hold on tight until both the AD/PD conference in Florence, IT and the ACC conference in San Francisco, both of which occur in the week of 3/6 to 3/13.

There could also be an embargo from the ACC in effect on RVX discussing the data they plan to present at ACC (https://www.expo.acc.org/acc13/public/Content.aspx?ID=3054&sortMenu=105004). Another possibility is that there is a peer reviewed publication that is already accepted and ready for publication that is part of this embargo, and if and when they present at ACC, there will be new information simultaneously presented as oral presentation, scientific publication, and press releases. Again, this is IMO. One key will be to watch for the RVX meeting abstract to be potenitally published online on March 7 in advance of the ACC meeting (https://accscientificsession.cardiosource.org/ACC/Science/Abstracts-General-Information.aspx). If we DON'T see an abstract from RVX on that list, then my aforementioned embargo scenario seems more likely.

With these two conferences coming up, I really don't see them releasing anything new before the second week of March.

Bullboard Posts