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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

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Comment by BearDownAZon Apr 23, 2013 10:52am
160 Views
Post# 21287833

RE: Abstract from upcoming EAS conference in June

RE: Abstract from upcoming EAS conference in June

I just looked over the final program for the ATVB 2013 conference once again. Although RVX is still not listed as presenting, I found these two very relevant poster titles.

 

181: BET Bromodomain Inhibition Suppresses Endothelial Inflammation and Atherosclerosis

Jonathan Brown, Qiong Duan, Gabriel Griffin, Brigham and Women's Hosp, Boston, MA; Ronald Paranal, Steven Bair, Dana Farber Cancer Inst, Boston, MA; Gail Newton, Andrew Lichtman, Brigham and Women's Hosp, Boston, MA; Andrew Kung, Columbia Univ, New York, NY; Francis Luscinskas, Brigham and Women's Hosp, Boston, MA; Tianlun Yang, Xiangya Hosp, Central South Univ, Changsha, China; Kevin Croce, Brigham and Women's Hosp, Boston, MA; James Bradner, Dana Farber Cancer Inst, Boston, MA; Jorge Plutzky, Brigham and Women's Hosp, Boston, MA 

.

427: Apoliporotein A-I Improves Glucose Tolerance and Enhances Insulin-Dependent and Insulin-Independent Glucose Uptake in the db/db Mouse Model of Type 2 Diabetes

Blake J Cochran, Shudi Tang, Kerry-Anne Rye, Univ of New South Wales, Sydney, Australia

.

181 of course sounds very relevant. 427 is the same group that I had previously noted has an apoAI/diabetes abstract at the June EAS meeting.

 

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