RE: Lipator You have to keep in mind that ASSURE is only a 6 month study. From a therapeutic perspective, patients taking RVX-208 will likely be taking it for years. So even if there is only modest plaque regression, one must remember that this is only occuring over 6 months. The degree of plaque regression over the course of years of RVX-208 treatment could be off the charts. So what we want from ASSURE is solid data showing any amount statistically significant plaque regression in 6-months.