RE:RE:RE:and what will this week bring to affect the stock lower Tgtbtroi, I don't find the trading unusual at all; there are 148 million shares outstanding. Many investors may consider the current situation ideal for tax loss selling. Waiting for reaction from the FDA and with the company itself now advising a partnership announcement unlikely before year end, this should be an opportunity to take the loss and safely wait 30 days to buy back, without fear of stock appreciation in the interim. And for others the risk level after receiving questions from the FDA may have become intolerable.
Shareholders not willing to take a loss may hope the FDA may be satisfied with the written explanation and a meeting may not be required, and/or a partner may still step up, particularly since the FDA appears to have indicated that at the very least, Compleo TID will be approved. Either of these events would provide a catalyst for the share price to rise substantially.
From Trimel's perspective they would obviously prefer both Compleo BID and TID be approved. One of the big selling points competitively speaking will be convenience, and taking something twice a day is obviously easier than taking something three times a day, assuming therapeutic levels of Testosterone in the blood are achieved with both.
On that point, the FDA's preference, if that is what it really is, for TID is curious. We heard in the conference call that between 30 - 35% of the BID group was titrated to TID. That means 65% - 70% of the BID group must have reached acceptable T blood levels. The response rate of Androgel, the leading competitor, is 52% - 62% and they are obviously long and well approved. Lilly's approved product Axiron has a response rate between 67% - 89%. What Trimel was trying to show with the small titrated group was that some of the patients who did not respond well BID would subsequently respond TID, where the response rate was called "strong". But as management indicated, it is impossible to know exactly where the FDA requires more explanation.
The question from the FDA was announced October 24 after market close. The biggest reaction selling - over 4 million shares - began the next day (see chart below). In the first 7 days after the announcement approx. 7.7 million shares traded - 5% of the float. One source pegs the current average daily volume for Trimel trades at 161,169, although with such huge fluctuations recently, this number is not terribly useful. The Short Position at the end of October remains negligible at 5,766 shares, no change after the FDA announcement.
2013-11-11 | T | TRL | 0.41 | 0.43 | 0.41 | 0.41 | | 25,167 | 20 | 0.41 | 0.425 | | 22,167 | | 1,500 | | | | 1,000 | | | | | | 500 | | | | | | |
2013-11-08 | T | TRL | 0.44 | 0.44 | 0.405 | 0.41 | -0.01 | 40,856 | 32 | 0.41 | 0.42 | | 26,856 | | 9,500 | | | | 4,500 | | | | | | | | | | | | |
2013-11-07 | T | TRL | 0.44 | 0.44 | 0.42 | 0.42 | -0.005 | 77,120 | 35 | 0.42 | 0.435 | | 53,120 | | 19,000 | | 3,000 | | 2,000 | | | | | | | | | | | | |
2013-11-06 | T | TRL | 0.44 | 0.44 | 0.425 | 0.425 | | 120,830 | 78 | 0.425 | 0.44 | | 84,830 | | 33,000 | | 2,500 | | 500 | | | | | | | | | | | | |
2013-11-05 | T | TRL | 0.405 | 0.445 | 0.40 | 0.425 | 0.015 | 251,725 | 115 | 0.425 | 0.43 | | 179,725 | | 50,500 | | 8,000 | | 12,500 | | | | | | 500 | | 500 | | | | |
2013-11-04 | T | TRL | 0.435 | 0.44 | 0.40 | 0.41 | -0.01 | 913,653 | 183 | 0.41 | 0.42 | | 876,153 | | 30,500 | | 1,000 | | | | | | | | | | 6,000 | | | | |
2013-11-01 | T | TRL | 0.415 | 0.43 | 0.40 | 0.42 | 0.02 | 208,300 | 99 | 0.415 | 0.425 | | 118,800 | | 24,000 | | 1,500 | | 10,000 | | | | | | 500 | | 53,500 | | | | |
2013-10-31 | T | TRL | 0.41 | 0.415 | 0.39 | 0.40 | -0.005 | 512,047 | 175 | 0.395 | 0.40 | | 431,547 | | 46,500 | | 9,000 | | 22,000 | | | | | | | | 3,000 | | | | |
2013-10-30 | T | TRL | 0.465 | 0.465 | 0.405 | 0.405 | -0.02 | 338,197 | 184 | 0.405 | 0.42 | | 208,197 | | 82,000 | | 9,500 | | 23,500 | | | | | | 500 | | 14,500 | | | | |
2013-10-29 | T | TRL | 0.465 | 0.475 | 0.42 | 0.425 | -0.025 | 481,935 | 210 | 0.425 | 0.44 | | 348,435 | | 95,500 | | 10,000 | | 22,000 | | 1,500 | | | | | | 4,500 | | | | |
2013-10-28 | T | TRL | 0.42 | 0.475 | 0.38 | 0.45 | 0.045 | 1,197,020 | 552 | 0.44 | 0.455 | | 769,520 | | 297,000 | | 70,500 | | 28,500 | | 10,500 | | | | 10,500 | | 10,500 | | | | |
2013-10-25 | T | TRL | 0.65 | 0.65 | 0.405 | 0.405 | -0.345 | 4,058,053 | 1,100 | 0.405 | 0.41 | | 2,639,553 | | 888,000 | | 347,000 | | 112,000 | | 66,500 | | | | 1,000 | | 4,000 | | | | |
2013-10-24 | T | TRL | 0.75 | 0.76 | 0.75 | 0.76 | | 3,620 | 6 | 0.74 | 0.77 | | 3,120 | | 500 | | | | | | | | | | | | | | | | |
2013-10-23 | T | TRL | 0.75 | 0.77 | 0.73 | 0.75 | | 47,420 | 37 | 0.75 | 0.76 | | 42,420 | | | | | | 5,000 | | | | | | | | | | | | |
2013-10-22 | T | TRL | 0.75 | 0.75 | 0.75 | 0.75 | -0.01 | 1,000 | 4 | 0.74 | 0.78 | | 1,000 | | | | | | | | | | | | | | | | | | |
2013-10-21 | T | TRL | 0.76 | 0.78 | 0.75 | 0.76 | 0.01 | 33,973 | 51 | 0.76 | 0.78 | | 28,473 | | 1,000 | | 4,500 | | | | | | | | | | | | | | |
2013-10-18 | T | TRL | 0.73 | 0.76 | 0.70 | 0.75 | 0.02 | 46,849 | 84 | 0.74 | 0.77 | | 44,849 | | | | 1,000 | | 1,000 | | | | | | | | | | | | |
2013-10-17 | T | TRL | 0.77 | 0.79 | 0.73 | 0.73 | -0.03 | 59,664 | 104 | 0.73 | 0.78 | | 49,664 | | 10,000 | | | | | | | | | | | | | | | | |
2013-10-16 | T | TRL | 0.78 | 0.78 | 0.76 | 0.76 | -0.04 | 1,600 | 5 | 0.76 | 0.79 | | 1,600 | | | | | | | | | | | | | | | | | | |
2013-10-15 | T | TRL | 0.75 | 0.80 | 0.75 | 0.80 | | 35,813 | 31 | 0.75 | 0.80 | | 21,313 | | 6,500 | | 3,500 | | 3,500 | | 1,000 | | | | | | | | | | |
2013-10-11 | T | TRL | 0.80 | 0.80 | 0.80 | 0.80 | 0.02 | 2,000 | 2 | 0.75 | 0.80 | | 1,500 | | | | 500 | | | | | | | | | | | | | | |
2013-10-10 | T | TRL | 0.78 | 0.80 | 0.77 | 0.78 | -0.01 | 30,850 | 20 | 0.78 | 0.80 | | 28,850 | | 2,000 | | | | | | | | | | | | | | | | |
2013-10-09 | T | TRL | 0.76 | 0.79 | 0.73 | 0.79 | 0.02 | 45,470 | 25 | 0.74 | 0.78 | | 43,470 | | | | 2,000 | | | | | | | | | | | | | | |
2013-10-08 | T | TRL | 0.80 | 0.80 | 0.77 | 0.78 | -0.03 | 9,340 | 11 | 0.77 | 0.79 | | 5,840 | | 3,500 | | | | | | | | | | | | | | | | |
2013-10-07 | T | TRL | 0.77 | 0.80 | 0.77 | 0.80 | 0.03 | 18,157 | 14 | 0.77 | 0.82 | | 16,657 | | 1,000 | | | | 500 | | | | | | | | | | | | |
2013-10-04 | T | TRL | 0.78 | 0.80 | 0.76 | 0.77 | -0.03 | 81,875 | 40 | 0.77 | 0.79 | | 78,875 | | 500 | | 2,000 | | 500 | | | | | | | | | | | | |
2013-10-03 | T | TRL | 0.80 | 0.80 | 0.79 | 0.80 | 0.01 | 31,086 | 15 | 0.79 | 0.80 | | 28,086 | | | | 3,000 | | | | | | | | | | | | | | |
2013-10-02 | T | TRL | 0.80 | 0.80 | 0.78 | 0.79 | | 13,300 | 14 | 0.78 | 0.79 | | 12,300 | | | | 1,000 | | | | | | | | | | | | | | |
2013-10-01 | T | TRL | 0.79 | 0.81 | 0.79 | 0.79 | -0.03 | 71,301 | 41 | 0.77 | 0.79 | | 59,801 | | 1,000 | | 10,500 |