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Presentation |
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Session |
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Wed, Apr 9, 8:00 AM - 12:00 PM
5011/1 - Cancer immunotherapy targeting CD47: Wild type SIRPaFc is the ideal CD47-blocking agent to minimize unwanted erythrocyte binding |
Robert A. Uger, Karen Dodge, Xinli Pang, Penka S. Petrova. Trillium Therapeutics Inc./Stem Cell Therapeutics Corp., Toronto, ON, Canada |
Poster Session
PO.IM02.02. Immune Checkpoint Inhibition
Wed, Apr 9, 8:00 AM - 12:00 PM |
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Mon, Apr 7, 1:00 - 5:00 PM
1911/6 - NF-?B mediated CD47 upregulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma |
Jessica Lo, Eunice Yuen Ting Lau, Irene Oi Lin Ng, Terence Kin Wah Lee. State Key Laboratory for Liver Research, Department of Pathology, Li Ka Shing Faculty of Medicine,The University of Hong Kong, Hong Kong |
Poster Session
PO.TB02.01. Cancer Stem Cell Phenotype and Function 1
Mon, Apr 7, 1:00 - 5:00 PM |
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Tue, Apr 8, 1:00 - 5:00 PM
4082/10 - CD47 blockade to enhance adaptive anti-tumor immune responses |
Katie L. Anderson, Daisuke Ito, Debra C. Lins, Julie M. Curtsinger, Matthew F. Mescher, Jaime F. Modiano. University of Minnesota, Minneapolis, MN |
Poster Session
PO.IM01.04. Adaptive Immunity and Immune Regulation
Tue, Apr 8, 1:00 - 5:00 PM |
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Mon, Apr 7, 1:00 - 5:00 PM
2434/5 - Therapeutic targeting of CD47 regulates cell bioenergetics and autophagy to reduce breast tumor growth and protect against anthracycline-mediated cardiac toxicity |
David R. Soto-Pantoja, John M. Sipes, Arunima Ghosh, Maria J. Merino, David D. Roberts. Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD |
Poster Session
PO.MCB09.05. Metabolic Pathways 2
Mon, Apr 7, 1:00 - 5:00 PM |
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Mon, Apr 7, 8:45 - 9:15 AM
PL02-02 - Investigating inhibition of the CD47 "don't eat me" signal to enable tumor phagocytic removal and augmented cross presentation to T cells |
. Stanford Univ. School of Medicine, Stanford, CA |
Plenary Session
PL02. Targeted Immunotherapy: Mobilizing the Immune System Against Cancer
Mon, Apr 7, 8:15 - 10:15 AM |
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Tue, Apr 8, 8:00 AM - 12:00 PM
3629/2 - Overcoming macrophage immunosuppression in small cell lung cancer with high-affinity SIRPa variants |
Kipp Weiskopf, Peter J. Schnorr, Nadine Jahchan, Aaron M. Ring, Roy L. Maute, Anne K. Volkmer, Jens-Peter Volkmer, Kenan C. Garcia, Julien Sage, Irving L. Weissman. Stanford University School of Medicine, Stanford, CA |
Poster Session
PO.IM02.06. Immune Modulation in the Tumor Microenvironment
Tue, Apr 8, 8:00 AM - 12:00 PM |
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Wed, Apr 9, 8:00 AM - 12:00 PM
5318/14 - LC-MS/MS quantification of proteins CD47 and SIRPA in cell subtypes selected by flow cytometry from blood |
Carmen Fernandez-Metzler1, Renold Capocasale2. 1PharmaCadence Analytical Services, Hatfield, PA;2Flowmetric, Doylestown, PA |
Poster Session
PO.MCB12.02. Proteomics
Wed, Apr 9, 8:00 AM - 12:00 PM |
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Tue, Apr 8, 1:00 - 5:00 PM
3886/2 - Clec12a: A new AML stem cell-associated antigen |
Viviana Guadagnuolo, Enrica Imbrogno, Andrea Ghelli Luserna di Rorà, Antonella Padella, Giorgia Simonetti, Emanuela Ottaviani, Cristina Papayannidis, Ilaria Iacobucci, Anna Ferrari, Simona Soverini, Giovanni Martinelli. L. & A. Seragnoli, Bologna, Italy |
Poster Session
PO.TB02.06. Cancer Stem Cell Phenotype, Function, and Targeting
Tue, Apr 8, 1:00 - 5:00 PM |
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Tue, Apr 8, 1:00 - 5:00 PM
3959/24 - Depleting macrophage or blocking cell fusion machinery ameliorates intestine fibrosis after radiation |
Ya-Hui Chang, Hui-Ju Ch’ang, Li-Mei Lin. National Health Research Institution, Tainan City, Taiwan |
Poster Session
PO.TB09.01. Modifiers and Predictors of Tumor Response to Radiation and Other DNA-Damaging Agents 1
Tue, Apr 8, 1:00 - 5:00 PM |
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Wed, Apr 9, 8:00 AM - 12:00 PM
4820/8 - Exploring metastatic capacity and targets on circulating epithelial cells (CEC) in early and late breast cancer |
Leo Habets, Sr.1, Bettina Frenken1, Ilham El Ghali1, Mahmoud Danaei2, Manfred Kusche2, Uwe Peisker3, Katharina Pachmann4. 1Metares e.V, Aachen, Germany; 2Brustzentrum Aachen Kreis Heinsberg, Aachen, Germany; 3Brustzentrum Aachen Kreis Heinsberg, Erkelenz, Germany; 4TZB Bayreuth, Bayreuth, Germany |
Poster Session
PO.TB04.09. Circulating and Disseminated Tumor Cells as Predictors of Tumor Metastasis
Wed, Apr 9, 8:00 AM - 12:00 PM |
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Tue, Apr 8, 8:00 AM - 12:00 PM
3044/13 - Cancer associated fibroblasts-derived HGF regulates cancer stem cell-like properties in hepatocellular carcinoma |
Yuen Ting Lau, Jessica Lo, Irene Oi Lin Ng, Terence Kin Wah Lee. The University of Hong Kong, Hong Kong |
Poster Session
PO.TB02.04. Cancer Stem Cell Phenotype and Function 2
Tue, Apr 8, 8:00 AM - 12:00 PM |
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Mon, Apr 7, 1:00 - 5:00 PM
2661/22 - Patient-derived breast cancer targeting heavy chain antibodies |
Charan Kumar V. Devarakonda1, Daniel Kita1, Kathryn N. Phoenix1, Dewey M. Magee2, Kevin P. Claffey1. 1University of Connecticut Health Center, Farmington, CT; 2Arizona State University, Tempe, AZ |