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biOasis Technologies Ord Shs V.BTI.H


Primary Symbol: BIOAF

Bioasis Technologies Inc. is a Canada-based biopharmaceutical company focused on research and development of technologies and products intended for the treatment of patients with nervous system, including central nervous system, diseases and disorders. The Company is engaged in the development of its xB 3 platform, which is a peptide-based technology, for the transport of therapeutic agents, in particular biological products, across the blood-brain barrier (BBB). It is focused on both orphan drug indications, including brain cancers, and rare genetic neurodegenerative diseases and neuroinflammatory conditions. The Company is also focused on its Epidermal Growth Factor (EGF) platform for treating rare and orphan neurodegenerative and neuroinflammatory disorders. EGF is a protein that stimulates cell growth and differentiation, notably for myelin producing cells. Its development programs include xB3-001: Brain Metastases, xB3-002: Glioblastoma and xB3-007: Neurodegenerative Disease.


GREY:BIOAF - Post by User

Post by neinsteinon Mar 12, 2014 3:28pm
217 Views
Post# 22315368

Licensing deals

Licensing dealsit's my understanding that many licensing deals announced are not always what they appear if you were to simply take for granted the initial press release. specifically the upfront dollar amounts. these 'large' payments are rarely actually a simple transfer of cash up front, but are tied to studies that need to occur long before we see the 'milestone' payments and of course royalties which come further down the road.

the inital studies look at certain variables such as dosing, efficacy, survival, etc. (i'm sure i've missed many)

as such i though it would be interesting to get some discussion going about what type of structures we could see and which structure(s) we believe to be the most attractive to BTI. maybe it's less money upfront and more money if and when a study de-risks the situation.  

for example i believe the efficacy study is usually the most important.  we have no idea what the collaborations have have tested. if they have not yet tested efficacy i would think the pharmas' willingness to part with substantial funds upfront will be somewhat muted.  

it seems to me that if BTI is confident of proving efficacy once it enters into licensing arrangements, that it would be in BTI's best interest to accept a lesser amount upfront, but to ensure an efficacy study is completed within a reasonbly short time period.  that is of course if BTI can negotiate the timeline and progression of studies post arrangement.

any thoughts, opinions or experience on this subject?


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