RE:RE:WHAT DID THE CC PERSON ACTUALLY SAY TO THE PRESS?Jkj, thanks as always. Let's hope it's addressed. There seems to be so many positive aspects to this compound...benefits to many health aspects beyond plaque reduction.
For example a posting from Biotech777..."Also keep in mind that plaque is a broad term. There are various types of plaque within the artery wall ranging from soft lipid plaques to fibro calcific plaques to fully calcified. RVX-208 only has an effect on soft lipid base plaques."
The following paragraph. "The good news is that the percentage of (plaque) reduction is less important. This type of therapy is not about improving blood flow, but rather reducing risk for heart attack. We know that most (apptox 70%) of heart attacks are caused by ruptured plaque. The type of plaque that is most likely to rupture is just happens to be soft lipid based plaque. This is why even with very low regression numbers, there can be improvements in clinical outcomes such as reductions in heart attacks. Soft lipid based plaques form pools called liid rich necrotic cores. Nearby certain scavenger cells express inflammatory compounds that destabilze the area. So reducing lipid content adjacent to these pools is important to stabilizing the lesion and reducing the chance of a heart attack".
So it looks like 208 and it's MACE results are supported by the biochemistry. Hope I understood this properly.
Toinv