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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Bullboard Posts
Comment by BearDownAZon Jul 22, 2014 10:25am
202 Views
Post# 22769147

RE:Lead Sponsor 15 Minutes of Fame

RE:Lead Sponsor 15 Minutes of FameLooks like its not just Dr. Norman Wong giving a 15 minute talk tomorrow on RVX-208 representing Resverlogix, but following Dr. Wong is Kevin McLure from Zenith giving a 15 minute talk on BET inhibitors, oncology and autoimmune disease.

https://epic-boston.com/agenda/day-one

10.25 RVX-208 a BET inhibitor that raises ApoA-I in human clinical trials

  • RVX-208 is a selective BET inhibitor that induces ApoA-1 gene transcription.
  • Preclinical data and data from human clinical trials are presented.
  • Post hoc analysis from the latest clinical trials are discussed
 

Norman Wong, CSO,Resverlogix Corp

..........................................................................................................................................................................................................

10.40 Developing Best in Class BET Inhibitors for Oncology & AI: from Discovery to the Clinic.

  • A robust discovery platform that has generated high potency BETi with desirable pharmaceutical properties.
  • ZEN-3365 was selected for clinical development for hematologic cancers and solid tumors and shows excellent preclinical efficacy.
  • In vivo proof of concept in multiple models of Autoimmune has been demonstrated.
 

Kevin G McLure, PhD, Senior Director of Translational Biology,Zenith Epigenetics Corp


Bullboard Posts