RE:RE:RE:MerckCasusF, You wrote: Has any of the research determined this to be an issue? Has Theralase published anything or made statements concluding that PDC uptake into tumors is not 100%. Where did this idea come from? Well, it might have come from the fact that TLT has done trials on 5mm tumors in mice! As someone mathematically went thru for you the other day, if you have a 10mm tumor and assuming it to be roughly cylindrical then the mass of the 10mm tumor is 8 times that of the 5mm (you'll recall from high school math that 2 dimensional objects are squared and 3 dimensional objects are cubed so to illustrate further, a 40mm tumor is 64 times the size of the 5mm one). Let's hope that there is complete dispersion of PDC but TLT has also spoken to dispersion in their trials. The idea of validating this in a large mammal while awaiting Ph1/2a results makes perfect sense. Try to keep up!