RE:A backhanded 20-fold target population estimate/concern....Hey RGonly. Nice to hear from you. Hope to run into you at the AGM. One more thing that was missed by HT, was $1,000 per dose is very light. Probably double that at least. I've heard numbers kicked around by ex staff of 20-30k for full course treatment. I don't think you could get that for front line treatment, as BCG is in the $1200/ dose range. (up to 6 doses are sometimes needed) Prices are going up for ALL BC drugs because of Merck shutting down BCG production and the ensuing shortage. "Using a database of historical prices over the past 3 years, 40mg of mitomycin c has increased over a 100% over the past year. This price increase is in concert with the BCG shortage." So pricing will be vey interesting in the valuation matrix once FDA approved. beech