TSXV:BTI.H - Post by User
Comment by
Hobberson Jan 15, 2015 10:46am
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Post# 23322913
RE:Getting through the BBB
RE:Getting through the BBB A little more on the previous post:
From Rick's Science Page:
AveXxis and Genzyme are both developing gene therapy approaches in which a harmless virus is genetically modified to express the missing SMN1 gene. This virus is unique in that it can be injected intravenously and still penetrate the blood brain barrier and enter into the critical motor neuron cells. In addition to entering motor neurons and other cells in the central nervous system the virus can enter into other tissues such as the liver, heart, kidneys, etc. This is a very promising approach that has produced stunning results in the survival of the mouse model of SMA type 1, giving them a nearly normal lifespan.
https://onegenefromperfect.com/?page_id=88