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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

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Comment by SanFrancisco99on Mar 26, 2015 1:52pm
131 Views
Post# 23565090

RE:RE: BLOG ADDITION

RE:RE: BLOG ADDITIONWeird coincidence but I just ran into an article (by chance actually) that mentioned Dr. Jorge Plutzky.

https://scienceblog.com/74594/way-inhibit-inflammation-blood-vessel-linings/#BBT7o8dWoxwQf5FU.97

Here's a quotation:

“By using tools that interrogate the entire genome, it has been exciting to uncover how inflammatory signals known to promote atherosclerosis employ BET bromodomain-containing proteins as an epigenetic means of directing entire programs of endothelial gene expression,” said co-corresponding senior authorJorge Plutzky of BWH Preventive Cardiology, an associate professor of medicine at Harvard Medical School (HMS). “BET bromodomain-containing proteins have been studied in cancer for some time, where they are in therapeutic trials, but now we have mechanistic evidence for how BETs and their inhibition can impact endothelial inflammation and atherosclerosis.”
Read more at https://scienceblog.com/74594/way-inhibit-inflammation-blood-vessel-linings/#RBS1g1jMBCy7pQCt.99




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