RE:RE:Plasminogen and (diabetic) chronic woundYou are absolutely right Bepando...plasminogen is the key for PLI. Everything will start to flow once we get the FDA approval for T1 hypoplasminogenia (derisking the whole PPPS platform for large investors).
I know it's way too early to discuss this but if plasminogen one day gets approved for treating serious chronic wounds, I wonder how PLI would address the huge need (in term of grams of plasminogen extracted per year). Given the size of serious chronic wounds market...and the fact that they will first have to address T1 plasminogen deficiency, that would probably be impossible for PLI to produce enough plasminogen IV dose with "only" one (or even with two) millions of liter per year...for both indication.
Well maybe this would be the start of a new era for the PPPS technology development. Who would try to extract it with the Cohn technology when the yield (for plasminogen) is only 35 % (purity is not known but it's fair to assume that it is lower than the 70 % obtained with PPPS).
M80