RE:RE:ORPHAN DRUG FACTSGV, the pumpertrasholes (which have thankfully now left this MB) will pump anything in hopes of scamming a rube...but ODD (which BTW as you note and which the rubes may not and the pumpers never will) is not approval..but the FDA etc have determined that various economic incentives need to be in place to attract research in hard to treat small groups...this enables smaller trials, rolling data submissions, etc. (on the trials side) and the exclusivity and high reimbursement rates...but as best i know (i follow SRPT who is doing ODD in DMD) these are very high risk challenges that would not be attempted without the incentives...DM seemed to be pumping an RVX ODD would only be a PIII but gotta disbelieve that one, unless they have some truly astonishing data in ASSURE or ASSERT and well DM is always pumping...but for a small market cap company like RVX this could be a nice price bump up