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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Bullboard Posts
Comment by BearDownAZon Oct 15, 2015 5:08pm
279 Views
Post# 24195758

RE:RE:RE:Unfortunate timing - Nicholls article on RVX - 09/15

RE:RE:RE:Unfortunate timing - Nicholls article on RVX - 09/15I had a couple of posts on the other board linked here and here that talked about this ASSURE article and another recent review.

ASSURE had to be published. This particular article was simply the Cleveland Clinic obligitory publication of the original primary and secondary endpoints. It mainly focused on the IVUS PAV and TAV data and change in apoAI and HDL. What is disappointing is that this article didn't mention MACE as best as I could tell from the abstract. It might mention it in the full text that I can't access. 5-point MACE was a pre-defined secondary endpoint. And as we know, the MACE data was the most exciting thing to come out of SUSTAIN/ASSURE and the basis for the upcoming Phase 3 BETonMACE!
Bullboard Posts