RE:CEO and COO must resigni agree,
CEO and COO failed miserably at two most important value driving objectives:
a) successful AdCom (miserable failure made worse by their lack of leadership at the event)
b) approval by the FDA (IMO in part driven by AdCom failure and IMO a positive AdCom would have resulted in approval)..
..they were hired to do a job and they failed, they weren't hired to design and run trials or sell TST or become some sort of hedge fund..
..they tried they failed they should be replaced to not do so makes a stench but IMO
.. as JPM old health care group = Consanance them yanks will force a change if not forthcoming