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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Bullboard Posts
Comment by toinv261on Aug 04, 2016 2:04pm
134 Views
Post# 25110955

RE:RE:RE:RE:Zenith Reorg

RE:RE:RE:RE:Zenith ReorgHey GV and others.

It is great to see that Don and team completed the Zenith name change and, as I call it, restructuring and they did it as promised and on time.

Of course we now have the issue of liquidity. It is difficult to determine what assets would generate value and interest in a Zenith IPO but there are a number of assets I can think of;
  1. If I recall they already have 1500 or 2400 compounds in their library.
  2. The zen3694 trial of metastatic castration resistant prostate cancer is now dosing.
  3. This trial is not double blind and therefore, as I understand it, results can be analysed as the trial progresses.
  4. Zenith like Resverlogix is a drug development platform or factory (if you will).
  5. They appear to have a 9 year lead in intellectual property development.
  6. It appears their approaches to BET inhibition probably has a wide range of indications.
  7. They have an excellent depth of scientific talent.
  8. There is the potential for orphan trials.
  9. We know that Zenith Capital owns rvx-208 royalties (and perhaps royalties on more RVX compounds). 
  10. In vitro testing completed to date is an asset.
  11. There may be existing patents.
  12. And I'm sure the list goes on.

So it may have an exciting future. Shares in Zenith Capital could represent an endless flow in royalties depending on how they structure the businesses under the Zenith Capital umbrella.
If they structure according to the "Star" molecule system as SanFran describes perhaps it creats a number of options;
  1. Each molecule or "Star" could be a separate IPO with Zenith Capital remaining private.
  2. They could sell each drug down stream with partners like Hepalink and others.
  3. Each compound may have appeal to specific BP targetting that area hence they could sell a compound to a BP and receive a royalty flow.

OR they could sell Zenith Capital and all of it's assets. Don had mentioned something like this in one of his updates.

I would speculate that they won't do this because Don said he would like to reward everyone on the team for their 16 years of dedication. However, this sort of implies that each employee actually owns shares in Zenith Capital and I doubt that that is true.

Anyway, I'm just thinking out loud here. I'm glad I hold many thousands of Zenith shares because there could be a huge future of royalties flowing. 

If the mCRPC trial begins to show early positive results it will lend credibility to both the RVX and Zenith brands. It could deliver on the revenue side sooner than BETonMACE.

GLTA. It is roasting in Muskoka and I am headed to the lake.
Cheers
Toinv


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