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Resverlogix Corp T.RVX

Alternate Symbol(s):  RVXCF

Resverlogix Corp. is a Canada-based late-stage biotechnology company. The Company is engaged in epigenetics, with a focus on developing therapies for the benefit of patients with chronic diseases. Its epigenetic therapies are designed to regulate the expression of disease-causing genes. The Company's clinical program is focused on evaluating its lead candidate apabetalone (RVX-208) for the treatment of cardiovascular disease and associated comorbidities, and post-COVID-19 conditions. RVX-208 is a small molecule that is a selective bromodomain and extra-terminal (BET) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. RVX-208 is a BET inhibitor selective for the second bromodomain (BD2) within the BET proteins. It partners with EVERSANA, to support the commercialization of RVX-208 for cardiovascular disease, post-COVID-19 conditions, and pulmonary arterial hypertension in Canada and the United States.


TSX:RVX - Post by User

Bullboard Posts
Comment by BearDownAZon Sep 01, 2016 2:02pm
202 Views
Post# 25200213

RE:RE:RE:THANKS F6- IS RVX-208 BEING SOL IN CHINA?? THOUGHTS??

RE:RE:RE:THANKS F6- IS RVX-208 BEING SOL IN CHINA?? THOUGHTS??"THANKS BEAR BUT WHERE DO THEY GET IT FROM?"

Most likely they synthesize it themselves. The structure is known and published, so chemists can synthesize it. 

"IF RVX HAS THE PATENT THEY MUST PAY A LICENSE OR OTHER FEE IN ORDER TO SELL IT."

There are many patented drugs currently in clinical trials that are synthesized and sold by chemical companies to be used in basic research. The structure of RVX-208 is known and published, so chemists can synthesize it. I do not know whether these chemical companies that sell RVX-208 had to pay any fee for the purpose of selling it for basic research. 

"WHAT CONSTITUTES RESEARCH PURPOSES......CAN JUST ANYBODY BUY IT FOR RESEARCH PURPOSES. I WANT SOME FOR MY PERSONAL RESEARCH; IS THAT ALLOWED."

If you have to ask, then you're not doing research. Even if you did want to buy some for "personal research" most if not all of these companies do not sell to patients. There's also a difference in production standards between research grade and clinical grade compounds, so you wouldn't want to do too much "personal research" with these. Also, if you were considering trying to buy some for "personal research", keep in mind you'll need 200 mg a day (100 mg twice a day) to duplicate the dosing regimen used in Phase 2 and Phase 3 trials. That sticker shock may dissuade you. These chemical companies probably make it on a small scale, resulting in a high cost/mg. 

"COULD BIG PHARMA IN CHINA GET IT AND COPY IT. " 

The structure is known and published, so chemists can synthesize it....even if they live in China.
Bullboard Posts