RE:Year end SP Predictions ?Generally speaking, the shorter the term, the harder to predict share price; the riskier the stock, the harder to predict share price. For Promis, it falls in the extremely risky AD drug development category. And therefore, it would be extremely sensitive to news, either positive or negative. At the end of the day, its price could be 0 or $60. Pick a number in the air for probability of success, let's say 1%, then your target share price would be around 60 cents. Based on the utility theory, risk averse people would like to pay much less than expected value, as a result, you might see something around 20 cents or even lower. It is essentially a lottery though you still call it an investment.