RE:Regular Asperin UseG1945,
First of all, you cite an article focused on aspirin and cancer mortality, and not aspirin and CVD. Does aspirin offer protection against cardiac events in high-risk patients? The American Heart Association, the American Stroke Association and the American Diabetes Association recommend the use of low-dose aspirin for prevention of cardiovascular disease in adults whose risk is sufficiently high for the benefits to outweigh the risks associated with treatment (e.g. bleeding). They suggest that a 10-year CVD risk of 6% to 10% is sufficient.
Aspirin is not a new drug and has likely been recommended to high-risk CVD patients for many years now even before launch of BETonMACE. I wouldn't be surprised if many of the physicians are already recommended patients enrolled in BETonMACE to take aspirin. Keep in mind that this is a randomized trial. Therefore, both placebo group (statin only) and RVX-208 group (statin plus RVX-208) would both potentially be recommended to take aspirin. So there shouldn't be any worry of aspirin use affecting BETonMACE in my opinion. Furthermore, if RVX-208 does what we all think and hope that it does, then the cardiovascular protection offered by RVX-208 is goign to far outweigh the protection offered by statins/aspirin alone.
BearDownAZ