RE:NewsTerrific news! Thanks enriquesuave, IvanVan Beethoven and LaserStock29.
Theralase research continues as the limitations of previous pdc's are eliminated one by one. They are digging into the requirements for destroying each cancer indication. The following particularly struck me:
' the='the' modular='modular' chemistry='chemistry' involved='involved' in='in' synthesizing='synthesizing' both='both' ru='ru' and='and' os='os' pss='pss' is='is' amenable='amenable' to='to' preparation='preparation' of='of' large='large' libraries='libraries' pdc='pdc' platforms='platforms' for='for' targeting='targeting' various='various' cancer='cancer' cells='cells' with='with' high='high' efficacy='efficacy' low='low' overall='overall' toxicity='toxicity' healthy='healthy' tissues.<='tissues.<'>
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Moreover, it has been demonstrated in this research that Os is a viable metal for building new therapeutic molecules, despite the pervasive notion that Os is too toxic for clinical applications.'>
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Full announcement:
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TORONTO, ON / ACCESSWIRE / April 6, 2017 / Theralase Technologies Inc. ("Theralase®" or the "Company") (
TLT.V) (OTC PINK: TLTFF), a leading biotech company focused on the commercialization of medical lasers to eliminate pain and the development of Photo Dynamic Compounds ("PDCs") to destroy cancer, announced today that its latest research has been accepted for peer reviewed publication, demonstrating that a new class of anti-cancer PDCs based on the metal Osmium ("Os") may be very effective in the destruction of cancer.
A new publication entitled, '>
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/pr.report/pAisaQln" href="https://pr.report/pAisaQln" rel="nofollow noopener" target="_blank">https://onlinelibrary.wiley.com/doi/10.1111/php.12767/epdf</a>" data-reactid="13" style="margin: 0px 0px 1em; color: rgb(38, 40, 42); font-family: "Helvetica Neue", Helvetica, Arial, sans-serif; font-size: 15px;" type="text">
https://onlinelibrary.wiley.com/doi/10.1111/php.12767/epdf
Researchers from: Theralase; Acadia University, Department of Chemistry; the University of North Carolina at Greensboro, Department of Chemistry and Biochemistry; the University of Toronto, Department of Medical Biophysics and Princess Margaret Cancer Centre, and University Health Network ('>
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Photo Dynamic Therapy (' canvas-atom='canvas-atom' canvas-text='canvas-text' mb(1.0em)='mb(1.0em)' mb(0)--sm='mb(0)--sm' mt(0.8em)--sm=' content=' cancer='cancer' remains='remains' a='a' major='major' global='global' issue,='issue,' requiring='requiring' the='the' advent='advent' of='of' new,='new,' efficient,='efficient,' and='and' affordable='affordable' treatments.=' data-reactid=' 17=' style=' margin:='margin:' 0px='0px' 1em;='1em;' color:='color:' rgb(38,='rgb(38,' 40,='40,' 42);='42);' font-family:='font-family:' "helvetica='"helvetica' =' type=' photo='photo' dynamic='dynamic' therapy='therapy' ("pdt"),='("pdt"),' which='which' uses='uses' light='light' activated='activated' photosensitizer='photosensitizer' ("ps")='("ps")' to='to' produce='produce' reactive='reactive' oxygen='oxygen' species='species' ("ros")='("ros")' in='in' sufficient='sufficient' quantities='quantities' destroy='destroy' cells,='cells,' has='has' been='been' established='established' as='as' an='an' effective='effective' treatment.='treatment.' 18=' style=' pdt"),='pdt"),'>
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One of the current limitations of PDT technologies, however, has been the scarcity of PSs that can be activated over a wide range of wavelengths, to allow treatment at various tissue depths, and produce few, if any, side effects. To address this shortcoming, three Os-based PSs were synthesized and their characteristics determined. Findings indicate that these PSs are able to be activated from Ultra Violet ('>
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Dr. Arkady Mandel, MD, Phd, D.Sc., Chief Scientific Officer of Theralase, stated that, ' canvas-atom='canvas-atom' canvas-text='canvas-text' mb(1.0em)='mb(1.0em)' mb(0)--sm='mb(0)--sm' mt(0.8em)--sm=' content=' petri='petri' dish='dish' cell='cell' studies='studies' have='have' demonstrated='demonstrated' that='that' these='these' os='os' pss='pss' longer='longer' wavelength='wavelength' activation='activation' and='and' efficacy='efficacy' in='in' red='red' nir='nir' light,='light,' both='both' normoxic='normoxic' (normal='(normal' oxygen)='oxygen)' hypoxic='hypoxic' (low='(low' conditions,='conditions,' making='making' them='them' highly='highly' suitable='suitable' for='for' destruction='destruction' of='of' solid='solid' core='core' cancer='cancer' tumours,='tumours,' which='which' generally='generally' present='present' with='with' cores.='cores.' =' type=' 21=' style=' margin:='margin:' 0px='0px' 1em;='1em;' color:='color:' rgb(38,='rgb(38,' 40,='40,' 42);='42);' font-family:='font-family:' "helvetica='"helvetica' previous='previous' ru-based='ru-based' pss,='pss,' such='such' as='as' tld-1433,='tld-1433,' been='been' able='able' to='to' be='be' activated='activated' by='by' laser='laser' when='when' combined='combined' transferrin,='transferrin,' but='but' are='are' more='more' blue='blue' green='green' relegating='relegating' their='their' use='use' clinical='clinical' applications='applications' superficial='superficial' nmibc.='nmibc.' 22=' style=' the='the' modular='modular' chemistry='chemistry' involved='involved' synthesizing='synthesizing' ru='ru' is='is' amenable='amenable' preparation='preparation' large='large' libraries='libraries' pdc='pdc' platforms='platforms' targeting='targeting' various='various' cells='cells' high='high' low='low' overall='overall' toxicity='toxicity' healthy='healthy' tissues.='tissues.' 23=' style=' moreover,='moreover,' it='it' has='has' this='this' research='research' a='a' viable='viable' metal='metal' building='building' new='new' therapeutic='therapeutic' molecules,='molecules,' despite='despite' pervasive='pervasive' notion='notion' too='too' toxic='toxic' applications.=' data-reactid=' 24=' style=' dr.='dr.' arkady='arkady' mandel,='mandel,' md,='md,' phd,='phd,' d.sc.,='d.sc.,' chief='chief' scientific='scientific' officer='officer' theralase,='theralase,' stated='stated' that,='that,' "the='"the' latest='latest' published='published' supports='supports' theory='theory' well='well' indicated='indicated' treat='treat' particularly='particularly' or='or' light='light' excitation='excitation' required='required' illuminate='illuminate' entire='entire' tumour='tumour' volume,='volume,' brain='brain' cancers.='cancers.' importantly,='importantly,' first='first' metal-based='metal-based' exhibit='exhibit' direct='direct' panchromatic='panchromatic' (activated='(activated' wide='wide' spectrum='spectrum' wavelengths)='wavelengths)' absorption='absorption' from='from' uv='uv' pdt.='pdt.' time,='time,' may='may' possible='possible' tune='tune' treatment='treatment' depth='depth' invasion='invasion' using='using' single='single' ps,='ps,' administration='administration' followed='followed' extended='extended' (that='(that' could='could' last='last' several='several' days),='days),' would='would' enable='enable' safest='safest' most='most' effective='effective' patient='patient' outcomes."='outcomes."' 25=' style='>
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