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ProMIS Neurosciences Inc PMN

Healthcare Biotechnology
ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

ProMIS Neurosciences Inc
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Comment by Actuarialon May 30, 2017 3:28pm
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Post# 26302067

RE:RE:RE:RE:Alzinova

RE:RE:RE:RE:AlzinovaI bet that Alzinova vaccine ALZ-101 works okay for mild AD but have little/no efficacy for mod/severe AD. We usually use vaccines to prevent disease but we seldom use vaccines for treatment - that's how most traditional vaccines work for human immune system. Therapeutic vaccines are generally lack of efficacy comparing with other treatments, i.e., antibody, molecules, etc.
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