Resetting the BS....I see DigiScammer hasn't posted today. No doubt he's working on some new BS. Like (in his best Arnold voice):
"This is PUUUUUUUUUNY! This shows a lack of confidence in BTI. Why MD didn't buy 500,000 shares yesterday!!!" Oh well, DigiScammer can always go back to reposting and reposting old news. Like yesterday, he reposted this
YEAR-OLD article on Herceptin and the heart.
He's trying again after
posting this bogus scare tactic just 3 weeks ago.
This particular BS is ironic because he doesn't realize that using Transcend to transport trastuzumab across the BBB results in relative
reduced distribution to the heart (as I
posted in response to his BS post 3 weeks ago).
P97-antibody conjugates and methods of use
US 20130183368 A1
Abstract The present invention provides p97-antibody conjugates and related compositions and methods, which may be used in any of a variety of therapeutic methods, including methods for the treatment of cancers such as Her2/neu-expressing and Her1/EGFR-expressing cancers.
....FIG. 10A shows the tissue/blood ratio of p97-trastuzumab conjugate for a variety of tissues. The ratios do not vary much between the two and eight hour time points; however,
the ratio (levels) of conjugate in heart tissue are significantly lower than other tissues (e.g.,
about 10× lower that lung and liver tissues)....
.... Further, because of the reduced distribution to heart tissues relative to other tissues, these data suggest that
conjugation to p97 might reduce the cardiotoxic effects of antibodies such as trastuzumab....