RE:NEWSBrillant results. AS application of 4050 has promising innovative medicine status in the UK and therefore will be able to trigger the EAMs process, leading to early market authorisation. A first stage of this process will be a Scientific opinion to be issued within 75 days after the process is triggered. I don't know where PLI is in this process but, it is possible that the UK could approve 4050 for Alstrom in H2 2018, with early compassionate use much earlier:-)
https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/520967/eams-operational-guidance.pdf