OTCPK:TRVN - Post by User
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GolongGekkoon Nov 20, 2017 2:29pm
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Therapeutic Advancements in Breakthrough Therapies...FYI
Therapeutic Advancements in Breakthrough Therapies...FYI Therapeutic Advancements in Breakthrough Therapies for Treating Chronic Pain Take aim at Reducing Opioid use
PALM BEACH, Florida, November 20, 2017 /PRNewswire/ --
A new study conducted by researchers at the University of New Mexico, involving medical cannabis and prescription opioid use among chronic pain patients, found a distinct connection between having the legal ability to use cannabis and significant reductions in opioid use. Cannabinoids found in the marijuana plant, cannabidiol (CBD) is the phyto-cannabinoid with perhaps the greatest potential for development as a therapeutic strategy for substance use disorders. In a recent article by researchers at Mt. Sinai School of Medicine points to animal models that suggest cannabidiol, found in cannabis, might reduce withdrawal symptoms as well as opioid-seeking behavior. Active in the markets today include: Veritas Pharma Inc. (CSE: VRT) (OTC: VRTHF), Perrigo Company plc (NYSE: PRGO). Cara Therapeutics, Inc. (NASDAQ: CARA), Trevena, Inc. (NASDAQ: TRVN), Collegium Pharmaceutical, Inc.
Trevena, Inc. (NASDAQ: TRVN) closed up over 3% on Friday at $1.71 by the market close trading over 500,000 shares. Travena in early November released news that it has recently submitted its New Drug Application (NDA) for OLINVOTM (oliceridine injection) to the U.S. Food and Drug Administration (FDA). OLINVO is the first G protein biased ligand of the mu opioid receptor, a new class of opioid receptor modulator, and the first pain program to receive Breakthrough Therapy designation from the FDA. The submission includes data showing that intravenous OLINVO demonstrated analgesic efficacy in all three dosing regimens tested in the two Phase 3 APOLLO pivotal efficacy studies. These trials were designed to support an indication for the management of moderate-to-severe acute pain in adult patients for whom an intravenous opioid is warranted.