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Trevena Inc TRVN

Trevena, Inc. is a biopharmaceutical company focused on the development and commercialization of medicines for patients with central nervous system (CNS) disorders. The Company has one approved product in the United States, OLINVYK (oliceridine) injection, indicated in adults for the management of acute pain severe enough to require an intravenous opioid analgesic and for whom alternative treatments are inadequate. The Company’s pipeline includes three differentiated investigational drug candidates: TRV045 for diabetic neuropathic pain and epilepsy, TRV250 for the acute treatment of migraine and TRV734 for maintenance treatment of opioid use disorder. TRV045 is a novel, highly selective sphingosine-1-phosphate subtype 1 (S1P1) receptor modulator being developed as a potential treatment for acute and chronic neuropathic pain secondary to diabetic peripheral neuropathy. TRV734 is a small molecule G-protein biased ligand of the mu opioid receptor (MOR).


OTCPK:TRVN - Post by User

Bullboard Posts
Post by GolongGekkoon Nov 20, 2017 2:29pm
61 Views
Post# 26998048

Therapeutic Advancements in Breakthrough Therapies...FYI

Therapeutic Advancements in Breakthrough Therapies...FYI

 Therapeutic Advancements in Breakthrough Therapies for Treating Chronic Pain Take aim at Reducing Opioid use

 

 


NEWS PROVIDED BY

MarketNewsUpdates.com 

08:30 ET


PALM BEACH, FloridaNovember 20, 2017 /PRNewswire/ --

 

A new study conducted by researchers at the University of New Mexico, involving medical cannabis and prescription opioid use among chronic pain patients, found a distinct connection between having the legal ability to use cannabis and significant reductions in opioid use. Cannabinoids found in the marijuana plant, cannabidiol (CBD) is the phyto-cannabinoid with perhaps the greatest potential for development as a therapeutic strategy for substance use disorders. In a recent article by researchers at Mt. Sinai School of Medicine points to animal models that suggest cannabidiol, found in cannabis, might reduce withdrawal symptoms as well as opioid-seeking behavior. Active in the markets today include: Veritas Pharma Inc. (CSE: VRT) (OTC: VRTHF), Perrigo Company plc (NYSE: PRGO). Cara Therapeutics, Inc. (NASDAQ: CARA), Trevena, Inc. (NASDAQ: TRVN), Collegium Pharmaceutical, Inc.
Trevena, Inc. (NASDAQ: TRVN) closed up over 3% on Friday at $1.71 by the market close trading over 500,000 shares. Travena in early November released news that it has recently submitted its New Drug Application (NDA) for OLINVOTM (oliceridine injection) to the U.S. Food and Drug Administration (FDA). OLINVO is the first G protein biased ligand of the mu opioid receptor, a new class of opioid receptor modulator, and the first pain program to receive Breakthrough Therapy designation from the FDA. The submission includes data showing that intravenous OLINVO demonstrated analgesic efficacy in all three dosing regimens tested in the two Phase 3 APOLLO pivotal efficacy studies. These trials were designed to support an indication for the management of moderate-to-severe acute pain in adult patients for whom an intravenous opioid is warranted.


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