RE:PBI 4050When an organ is damage, collagen goes in in the damage area and eventually transform into fibrosis tissu.
Skin is an organ.
Stretch mark are the result of skin being broken and same thing happen, collagen turns into fibrosis tissu and for skin, this is stretch mark and scars .
If 4050 and Plasminogen controls the healing and avoid fibrosis in organ, then why it would not also have an effect on skin scar such as stretch mark?
Plasminogen IV given to severe burned pork skin to keep the level of Pg during the healing process helped avoid the nasty severe burn scars on the pork skin on the animal trial.
If the same effect of PG and maybe 4050 (as it is an anti-fibrosis cumpound) is observe during the healing of the skin on human patient, it will be another huge application for Ryplazim and 4050.
Prometic is already planning to use Ryplazim IV in clinical trial for severe burns in order to heal faster and also to avoid burn scars.
IF I would be a patient with a severe burn or with a nasty scar from a recent chirurgy, I would pay whatever the price to get ryplazim IV or 4050 to avoid the scaring. (I already think of off-label for severe burns)
And a lot of women would love to have 4050 when they are pregnant to avoid stretch mark.
Time (and trials) will tell.
Eric