GREY:ATBPF - Post by User
Comment by
Actuarialon Mar 24, 2018 9:14pm
93 Views
Post# 27776631
RE:ATE Longs: Read posts carefully!
RE:ATE Longs: Read posts carefully!https://www.forbes.com/sites/matthewherper/2016/11/13/controversial-study-of-celebrex-raises-concerns-about-naproxen-ibuprofen/#6fc596095646
FitzGerald makes several points about Precision, which he says should be called Imprecision, aside from its ability to keep patients from stopping their medicines. First, he argues, it’s not a fair fight: the 200-milligram dose of Celebrex used in the study is less effective and has fewer side effects than the doses of the other drugs: 852 mg, on average, for naproxen and 2,045 mg for ibuprofen. (Over-the-counter doses are 660 mg and 1200 mg, respectively; Bayer says 80% of patients take less than 440 mg of Aleve a day.)
Also, FitzGerald argues, naproxen and ibuprofen can interfere with the function of aspirin, which prevents heart attacks, while Celebrex doesn’t. Nissen says analyses of his data don’t show that, but they only include whether patients were taking Aleve at the start of the study