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Trevena Inc TRVN

Trevena, Inc. is a biopharmaceutical company focused on the development and commercialization of medicines for patients with central nervous system (CNS) disorders. The Company has one approved product in the United States, OLINVYK (oliceridine) injection, indicated in adults for the management of acute pain severe enough to require an intravenous opioid analgesic and for whom alternative treatments are inadequate. The Company’s pipeline includes three differentiated investigational drug candidates: TRV045 for diabetic neuropathic pain and epilepsy, TRV250 for the acute treatment of migraine and TRV734 for maintenance treatment of opioid use disorder. TRV045 is a novel, highly selective sphingosine-1-phosphate subtype 1 (S1P1) receptor modulator being developed as a potential treatment for acute and chronic neuropathic pain secondary to diabetic peripheral neuropathy. TRV734 is a small molecule G-protein biased ligand of the mu opioid receptor (MOR).


OTCPK:TRVN - Post by User

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Post by GolongGekkoon May 01, 2018 8:54pm
194 Views
Post# 27967609

TRVN - Licenses CHINA!!! ( Trump voice OK here!) BAM!!

TRVN - Licenses CHINA!!! ( Trump voice OK here!) BAM!!

Trevena Inc. and Jiangsu Nhwa Pharmaceutical Co. Ltd Announce License Agreement for Oliceridine in China

News Provided by GlobeNewswire2018-05-01


– Nhwa granted a license to develop, manufacture, and commercialize oliceridine in China –

– Trevena to receive upfront and milestone payments and royalties –

CHESTERBROOK, Pa. and XUZHOU, China, May 01, 2018 (GLOBE NEWSWIRE) -- Trevena, Inc. (NASDAQ:TRVN) and Jiangsu Nhwa Pharmaceutical Co. Ltd. (Shenzhen Stock Exchange:002262) announced today that they have entered an exclusive license agreement for the development and commercialization of Trevena’s investigational product oliceridine.  Under the agreement, Trevena expects to receive near-term payments of $5.5 million, including an upfront payment of $2.5 million and a milestone payment of $3.0 million upon regulatory approval of oliceridine in the United States, as well as additional approval and commercialization milestones and 10% royalties on all product sales in China.  Oliceridine is currently under review by the U.S. Food and Drug Administration for potential approval in the United States for the management of moderate-to-severe acute pain.

“Nhwa is an ideal partner for the development and commercialization of oliceridine in China,” said Maxine Gowen Ph.D., President and CEO of Trevena.  “With a strong track record of developing and commercializing medicines targeting the CNS, including anesthetics and IV opioid analgesics for the hospital market, Nhwa is well positioned to introduce innovative products like oliceridine to the Chinese market.  We look forward to working with their team to make oliceridine a successful product in China.”

“Improving patients’ quality of life is one of Nhwa's primary goals,” said Mr. Jiaquan Sun, CEO of Nhwa. “We recognize that the safety and tolerability of medicines is very important to postoperative patients and caregivers.  We believe that oliceridine, which was designed to improve opioid pharmacology with a new mechanism of action, once approved, will provide an important and welcomed treatment option in China for patients suffering postoperative pain. Oliceridine also will add to our already-strong portfolio of anesthetic and analgesic products. We appreciate the opportunity to work with Trevena and its successful and proven team, and we believe that our teams are well poised for a successful collaboration as we work through the regulatory process to bring this important product to the Chinese market.” 

About Trevena

Trevena, Inc. is a biopharmaceutical company focused on providing better, safer therapies to patients in pain.  The Company has leveraged breakthrough science to discover and develop its investigational product, oliceridine injection, for the management of moderate-to-severe acute pain.  Oliceridine has been granted Breakthrough Therapy designation by the U.S. Food and Drug Administration, and is intended to provide healthcare providers an innovative new option for patients who require an intravenous opioid. The Company also has an early stage pipeline of new chemical entities targeting novel mechanisms of action, including TRV250 for acute migraine, neuropathic pain, and other indications. 

About Jiangsu Nhwa Pharmaceutical Co.Ltd

Jiangsu Nhwa Pharmaceutical Co., Ltd., is a Chinese pharmaceutical company committed to setting new standards in CNS healthcare. Nhwa endeavors to provide innovative, high quality medicines to CNS patients with serious unmet medical needs. Nhwa offers a growing portfolio of more than 100 marketed products covering more than 6000 hospitals throughout China, including antipsychotics, anesthetics and analgesics, and neurological products. For more than 60 years, Nhwa has focused on CNS medicine, and every member of Nhwa's approximately 3,000-strong workforce is dedicated to improving patient health and outcomes.

 

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