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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

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Post by retiredcopon Aug 11, 2018 10:32am
77 Views
Post# 28444458

Where should the gov't money go

Where should the gov't money go

SENATE CONSIDERS ALZHEIMER’S BILL

AUGUST 3, 2018

The U.S. Senate is considering a bill, the Building Our Largest Dementia Infrastructure for Alzheimer’s (BOLD) Act, to increase programs for Alzheimer’s patients and their caregivers.

At a meeting of the Senate Special Committee on Aging on June 19, lawmakers discussed the bill, introduced in November 2017 by Sen. Susan Collins (R-ME) and Sen. Catherine Cortez Masto (D-NV), with no one stating opposition to the legislation.

Alzheimer’s disease is the sixth-leading cause of death in the United States. The BOLD Act is one of the first large-scale congressional initiatives to address the disease from multiple angles. According to Alzheimer’s Impact Movement, the BOLD Act would establish Alzheimer’s Centers of Excellence around the country, provide funding to state and local organizations to foster early detection, and support an increase in collection and analysis of Alzheimer’s data.

‘A Well-Meaning Attempt’

Edward Hudgins, research director at The Heartland Institute, which publishes Health Care News, says despite bipartisan support and noble intentions, the BOLD Act is not the answer for patients suffering from Alzheimer’s and dementia. The FDA’s lengthy and daunting approval process for new Alzheimer’s drugs and treatment options is the main roadblock preventing patients from accessing new methods of care that show great promise in combating Alzheimer’s and dementia, Hudgins says.

Allowing patients greater access to experimental care would help spread innovative new treatments better than the proposed legislation, Hudgins says.

“The BOLD Act legislation currently before the U.S. Congress is a well-meaning attempt to provide services for Alzheimer’s sufferers and public information,” Hudgins said. “But adding another government program does not get to the root of the problem. The most promising work on Alzheimer’s is found in bio-hacking and tissue-based research such as the new stem-cell treatment offered in Japan.”

Sees Promise in Technologies

Hudgins says the key to treating Alzheimer’s and other persistent diseases is to allow people to try emerging, innovative treatment options.

“As researchers better understand the nature of the disease, they now have a technology that could allow them to engineer cells, possibly to stop or even reverse the disease or to regrow damaged brain cells,” Hudgins said. “Also promising is work on nanotech implants and brain-computer interfaces. Companies like Kernel or Elon Musk’s Neuralink seek to create implants to replace damaged parts of the brain or, through a ‘neural lace,’ connect the brain to computers to enhance cognitive abilities.

“Government should not stand in the way of such promising innovations,” Hudgins said.

Ashley Pappas (apappas.heartland@gmail.comwrites from Chicago, Illinois.

 

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