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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by Jefferam1on Aug 29, 2018 9:35am
144 Views
Post# 28534747

RE:RE:RE:NR: Antibe Provides Scientific Report on ATB-346

RE:RE:RE:NR: Antibe Provides Scientific Report on ATB-346I guess silver lining, if they can have same cox supression at lower dosage like 150 or 200 mg, perhaps the liver side effects will be even lower.
They seem to say "mild transient elevations of liver transaminases that were not of clinical concern."
But all the same if they can be just as effective with lower dosage I'd feel so much better.

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