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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Comment by Jefferam1on Apr 08, 2019 1:53pm
257 Views
Post# 29597675

RE:RE:RE:Health Minister

RE:RE:RE:Health Minister Hey all, everything is availble in the Sedar documents. Please do DD.
First off 14 day per person but they will be doing staggared enrolment. Difficult to predict first person to start the trial to last person, but it would be reasonable to think it could be 30-90 days apart. 
If you are serious about this investment you should all read the following:

Feb 22 2019

10:41:17 ET

 

Final short form prospectus - English

PDF

270 K 



Very good details with timelines here. which includes: A top-line data read-out of the Phase 2B dose-ranging, efficacy study for ATB-346 is expected in calendar Q3 2019.


Also you should be reading the MD&As - you'd see the details of the milestone payments are in the "Three and Dix months ended Sept 30, 2018" MD&A

Under the terms of license agreement 2 Antibe will be issued payment upon achievement of the following milestones: • US$1,000,000 upon receipt of regulatory approval from the Food and Drug Administration in the USA; • US$1,000,000 upon market launch of ATB-346 or the first offer for sale of ATB-346 in the Region; • US$1,000,000 upon total net sales in the Region exceeding US$5,000,000 for the first time; • US$1,000,000 upon total net sales in the Region exceeding US$10,000,000 for the first time; • US$1,000,000 upon total net sales in the Region exceeding US$20,000,000 for the first time; • US$1,000,000 upon total net sales in the Region exceeding US$30,000,000 for the first time; • US$1,500,000 upon total net sales in the Region exceeding US$40,000,000 for the first time; and • US$1,500,000 upon total net sales in the Region exceeding US$50,000,000 for the first time


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