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Skye Bioscience Inc SKYE

Skye Bioscience, Inc. is a clinical-stage biotechnology company focused on the discovery, development and commercialization of novel classes of therapeutic drugs that modulate the endocannabinoid system. The Company's clinical assets focus on the modulation of cannabinoid receptor 1 (CB1) to provide novel treatments and alternatives for diseases caused by metabolic disorders, inflammation, fibrosis and neurodegeneration, such as obesity and glaucoma. Its Phase 2 clinical candidates include nimacimab, a negative allosteric modulating antibody that inhibits peripheral CB1 receptors, being developed for the treatment of obesity and SBI-100 Ophthalmic Emulsion (SBI-100 OE), a CB1 agonist (activator), being developed for the treatment of glaucoma and ocular hypertension. The Company's Phase 2 study in obesity is designed to evaluate nimacimab's weight loss potential either as a single agent or in combination with a glucagon-like peptide-1 (GLP-1) agonist like semaglutide.


NDAQ:SKYE - Post by User

Bullboard Posts
Post by Frost39on Jun 01, 2019 5:29pm
115 Views
Post# 29791587

Fantastic news!

Fantastic news!   Emerald Bioscience Secures “All Fields” Licenses for Cannabinoid Derivatives Developed by University of Mississippi 
GlobeNewswire•May 29, 2019 
Licenses Permit Emerald to Develop THC-Prodrug and CBD-Analog for Any Therapeutic Indication by Any Route of Administration for Human and Veterinary Use 

LONG BEACH, CA, May 29, 2019 (GLOBE NEWSWIRE) -- via NEWMEDIAWIRE – Emerald Bioscience, Inc. (EMBI), a biopharmaceutical company focused on bioengineered cannabinoid-based therapeutics to address global medical indications, has signed licenses covering “all fields of use” pertaining to proprietary cannabinoid- derivative molecules developed by the University of Mississippi (UM), including a prodrug of tetrahydrocannabinol (THCVHS) and analog of cannabidiol (CBDVHS) being developed to treat ocular diseases. 

These “all fields” licenses permit EMBI to expand its proprietary therapeutic reach to a variety of diseases affecting other organ systems in both humans and animals. They also permit formulations for a variety of routes of administration, including but not limited to ocular, oral, transdermal, rectal and vaginal suppositories, and inhalational delivery, as covered in issued patents. 

“Emerald Bioscience is delighted to expand beyond the eye with this opportunity to develop these unique molecules into therapies that may address a spectrum of diseases,” noted Brian Murphy, MD, CEO and Chief Medical Officer of EMBI. “The versatility in administration enabled by these licenses and patents supports the Company’s approach of advancing precision medicine: delivering needed medication to a target organ in order to optimize safety and efficacy.” 

EMBI previously announced bioavailability data related to the analog of CBD indicating potential use in the management of metabolic diseases and fibrotic disorders of the liver, as well as published research demonstrating the analgesic effect in validated animal models of pain syndromes like neuropathy. 

Additionally, EMBI welcomed the recent DEA decision not to classify its CBD analog as a controlled substance, thereby enhancing the potential speed and scope of developmental options. 

The Company had previously licensed the THCVHS and CBDVHS molecules exclusively for ocular diseases and looks forward to continuing its relationship with the University of Mississippi, which has a fifty-year history of leadership in research and discovery related to cannabinoid chemistry and physiology. EMBI plans on working to establish strategic partnerships to expedite development of these candidate products and continue development of its ocular therapeutic candidates into the clinic. 

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