GREY:ATBPF - Post by User
Comment by
skibum45on Jul 29, 2019 8:40pm
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Post# 29972876
RE:A$$ u me!
RE:A$$ u me!don't think MM is pumping.... they're just trying to stimulate discussion and enthusiastic about prospects as a lot are. It's difficult to overstate the potential of Antibe if effectiveness proves similar to existing NSAIDs, favorable gastrointestinal profile persists, AND no significant new side effects discovered (eg. cardiac risk associated with some of the COX-2 inhibitors such as Vioxx). Apart from NSAIDs there are really very limited options for chronic pain. The ulcer risk has always been a massive roadblock for chronic NSAID use. Other drugs? ...acetaminophen --- mildly better than placebo... narcotics (including new synthetics like tramadol) -- addictive, tolerance inducing and simply don't work for chronic pain because of tolerance ... others such as gabapentin, pregabalin, duloxetine, etc. etc. are riddled with side effects and minimal evidence for benefit to a point that they will never be widely used. NSAIDs work.... just they destroy your stomach with chronic use. If ATE.V has solved (or even significantly improved) on this, the potential seems massive. Seems worth a stab to me. Excited to see the trial results.