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ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a development stage biotechnology company. The Company is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA), an alpha-synucleinopathy. Its proprietary target discovery engine applies a thermodynamic, computational discovery platform - ProMIS and Collective Coordinates - to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product portfolio includes PMN310 / Amyloid-beta, PMN267 / TDP-43, and PMN442 / Alpha-synuclein. The Company plans to investigate additional synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Its wholly owned subsidiary is ProMIS Neurosciences (US) Inc.


NDAQ:PMN - Post by User

Bullboard Posts
Post by retiredcopon Sep 12, 2019 11:43pm
172 Views
Post# 30122429

Info on biomarkers

Info on biomarkersThe ability to detect neurological biomarkers at ultra-low levels, which have traditionally only been detectable in cerebrospinal fluid, has the potential to transform the way brain injuries and diseases are diagnosed.
Simoa assays can detect neurological biomarkers, such as Neurofilament Light (NfL),Tau, GFAP and several otohers associated with brain injury and disease. With Simoa, these informative markers can be detected at much earlier stages, in blood, serum or plasma, enabling better understanding of the long-term effects and disease pathology without invasive measures.Quanterix  has a strategic focus in neurodegeneration, neuroinflammation, traumatic brain injuries (TBI) and multiple sclerosis (MS)  and is working with a rapidly growing network of academic researchers and pharmaceutical and biotech partners to drive advancements in head health research.

NEUROLOGY ASSAYS
Available for Scientific Research
Alpha-Synuclein
Aβ40
Aβ42
BDNF
GFAP
MMP-9
Neuro 4-Plex B
Neurology 2-Plex A (Tau, Aβ42)
Neurology 3-Plex A (Tau, Aβ42, Aβ40)
Neurology 4-Plex A (NF-light®, Tau, GFAP*, UCHL-1*)
NF-light®
NF-light® Advantage Kit (SR-X)
NSE
P-Tau 181
P-Tau 231
pNF-Heavy
Tau
Tau (mouse)
TDP-43
UCH-L1
 

Bullboard Posts