Join today and have your say! It’s FREE!

Become a member today, It's free!

We will not release or resell your information to third parties without your permission.
Please Try Again
{{ error }}
By providing my email, I consent to receiving investment related electronic messages from Stockhouse.

or

Sign In

Please Try Again
{{ error }}
Password Hint : {{passwordHint}}
Forgot Password?

or

Please Try Again {{ error }}

Send my password

SUCCESS
An email was sent with password retrieval instructions. Please go to the link in the email message to retrieve your password.

Become a member today, It's free!

We will not release or resell your information to third parties without your permission.
Quote  |  Bullboard  |  News  |  Opinion  |  Profile  |  Peers  |  Filings  |  Financials  |  Options  |  Price History  |  Ratios  |  Ownership  |  Insiders  |  Valuation

ProMIS Neurosciences Inc PMN

ProMIS Neurosciences Inc. is a clinical-stage biotechnology company. It is focused on generating and developing antibody therapeutics selectively targeting toxic misfolded proteins in neurodegenerative diseases such as Alzheimer’s disease (AD), amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA). Its proprietary target discovery engine applies a thermodynamic, computational discovery platform-ProMIS and Collective Coordinates-to predict novel targets known as Disease Specific Epitopes on the molecular surface of misfolded proteins. Using this approach, the Company is developing novel antibody therapeutics for AD, ALS and MSA. Its product candidates are PMN310, PMN267, and PMN442. The PMN310 is a monoclonal antibody designed to treat AD by selectively targeting toxic, misfolded oligomers of amyloid-beta. PMN267 product candidate targeting ALS. PMN442 is a drug candidate being developed for MSA designed to selectively target and protect against pathogenic a-syn species.


NDAQ:PMN - Post by User

Bullboard Posts
Comment by Haidukon Sep 15, 2019 4:50pm
220 Views
Post# 30128802

RE:RE:Next PP forthcoming…

RE:RE:Next PP forthcoming…
@ G1945V: thank you for your feedback.

PMN got my interest in the early months of 2016 (Alzheimer disease). Substantial progresses were made in 2016 and 2017, but since then, management keeps repeating the same old story (with few advances in the other diseases).

While I still believe in PMN, it appears that the next steps (for all diseases) depend on (the (availability of) the Biomarkers, as a preliminary condition to start a clinical study. I will not contest that this conceptual approach might provide major benefits (“rapid and cost effective”) and might become the standard in the years to come.

However, those biomarkers are not yet available (“could generate clinical data in a 2-4 year timeframe”) and it appears to me (but I recognize my entire lack of competence in this regard) that the resulting data (proof of concept, before Phase 1) will confirm or contradict the initial assumptions but not necessarily evidence that PMN has a cure for those diseases…

So, if someone has a better understanding, I will greatly appreciate some valuable inputs.

I concur with your comments about dilution but, except if a partnership deal is arranged (”Near term (3-12 month)”), I’m afraid that, what I call the “stockholder boredom syndrome”, might soon emerge (alternatively will continue).

Having said that, I have been proven wrong so many times....

Good Luck To All!
Bullboard Posts