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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Healthcare
Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Antibe Therapeutics Inc(Pre-Merger)
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Comment by Stockfshron Nov 09, 2019 8:52pm
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Post# 30332260

RE:RE:RE:RE:Frustrating week.

RE:RE:RE:RE:Frustrating week. My understanding, after watching the youtube video attached to Actuarial's post #30324160, is that studies so far show that ATB-346 with naproxen and H2S requires a significantly smaller dosage than naproxen alone in order to achieve the same COX reduction. COX is the main target enzyme for the anti-inflammatory and analgesic effects of NSAIDs. So less NSAIDS for the same pain reduction is of course a very, very good thing...
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