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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Healthcare
Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Antibe Therapeutics Inc(Pre-Merger)
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Comment by Actuarialon Nov 29, 2019 10:38am
117 Views
Post# 30405418

RE:On a happier(?) note ...

RE:On a happier(?) note ...Tanezumab, 2.5mg doesn't work, 5mg cause joint problem, 7.1 vs. 1.5 (NSAIDs arm). That's statistical significant.

qwerty22 wrote: ... (if you enjoy other peoples misery), Tanezumab, a new class of pain killer in OA going thru final development stage just got a huge safety issue. This was a much anticipated drug getting lots of attention and a potential 346 competitor looks like it'll be scrapped for OA now. You think todays news was bad, imagine something like that!

https://www.mdedge.com/rheumatology/article/213000/osteoarthritis/tanezumab-posts-higher-safety-event-rate-nsaids-over-1


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