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Theratechnologies Inc T.TH

Alternate Symbol(s):  THTX

Theratechnologies Inc. is a Canada-based clinical-stage biopharmaceutical company. The Company is focused on the development and commercialization of therapies addressing unmet medical needs. It markets prescription products for people with human immunodeficiency viruses (HIV) in the United States. The Company's research pipeline focuses on specialized therapies addressing unmet medical needs in HIV, nonalcoholic steatohepatitis (NASH) and oncology. Its medicines include Trogarzo and EGRIFTA SV (tesamorelin for injection). Trogarzo (ibalizumab-uiyk) injection is a long-acting monoclonal antibody which binds to domain 2 of the CD4 T cell receptors. EGRIFTA SV (tesamorelin for injection) is approved in the United States for the reduction of excess abdominal fat in people with HIV who have lipodystrophy. Its portfolio includes Phase I clinical trial of sudocetaxel zendusortide (TH1902), a novel peptide-drug conjugate (PDC), in patients with advanced ovarian cancer.


TSX:TH - Post by User

Bullboard Posts
Post by Greenviolinoon Dec 09, 2019 3:33pm
240 Views
Post# 30437017

Question

Question

It appears most of Th's SP past phenomenal run stems from Trogarzo expectations. First, a phase while Taimed was already in a Phase III study, and a second fueled by bullish Trogarzo sales.
Egrifta sales had a minor effect on the SP in this rise all along.
Now, the investor is basically asked to renew its confidence in Egrifta under a possible NASH-related Phase III study, based on hopeful results from Grinspoon's research.
I fully appreciate this logic.
However, I keep lingering on the following question: how is it, given all the years patients have been 
taking Egrifta, that Th's scientific team has never been able to remotely establish a correlation between the condition of Lipo dystrophy and that of the liver? Is it beacuse no patient had their liver condition examined throughout the time they were on Egrifta, or because the dosage used by Grinspoon is totally different from that used by a typical Egrifta user? 
Confidence in Egrifta's potential will be key in the next few quarters, as Trogarzo sales will increase more moderately than initially expected.

Bullboard Posts