Grace Therapeutics, Inc GRCE

Healthcare Biotechnology

Grace Therapeutics, Inc., formerly Acasti Pharma Inc., is a late-stage biopharma company with drug candidates addressing rare and orphan diseases. Its therapeutic pipeline consists of three clinical-stage drug candidates supported by an intellectual property portfolio of over 40 granted and pending patents in various jurisdictions. Its lead drug candidate, GTX-104, is a clinical-stage, novel, injectable formulation of nimodipine being developed for intravenous (IV) infusion in aneurysmal subarachnoid hemorrhage (aSAH) patients to address significant unmet medical needs. GTX-104 provides a convenient IV delivery of nimodipine in the intensive care unit, eliminating the need for nasogastric tube administration in unconscious or dysphagic patients. Its other pipeline drug candidates include GTX-102, which is an oral-mucosal betamethasone spray for the treatment of Ataxia Telangiectasia and GTX-101, which is a topical bio adhesive film-forming bupivacaine spray for Postherpetic Neuralgia.

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Grace Therapeutics, Inc

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Post by hydrocarbsson Jan 13, 2020 9:56am

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Post# 30545897

The placebo in both Trilogy trials

Trilogy trials plural, both use corn starch as the placebo.

From the 2Q CC Nov 2019

And as previously disclosed, the placebo we’re using in the TRILOGY studies is simple cornstarch, which is inert, and consequently is expected to have a neutral effect on key biomarkers of patients in the placebo group, and furthermore unlike mineral oil, cornstarch has no known effect on statin absorption or on statin efficacy.

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