RE:RE:RE:RE:here we go"No-brainer approval to me."
I'm not sure if you are referring to application for breakthrough therapy status or NDA/MAA approval with FDA/EMA. Keep in mind these SGLT2i and/or DPP4i are still a post-hoc analysis, and not pre-specified. Post-hocs are never "no brainers." Although not impossible to get FDA/EMA approval w/o another trial, the more probable scenario would be further clinical development prior to FDA/EMA approval.
BDAZ