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Antibe Therapeutics Inc(Pre-Merger) ATBPF

Antibe Therapeutics Inc. is a clinical-stage biotechnology company. The Company is leveraging its hydrogen sulfide (H2S) platform to develop therapies to target inflammation arising from a range of medical conditions. The Company’s pipeline includes assets that seek to overcome the gastrointestinal ulcers and bleeding associated with nonsteroidal anti-inflammatory drugs (NSAIDs). Its lead drug, otenaproxesul, is in clinical development as an alternative to opioids and NSAIDs for acute pain. Its second pipeline drug, ATB-352, is being developed for a specialized pain indication. The Company also focuses on inflammatory bowel disease (IBD). Otenaproxesul combines a moiety that releases hydrogen sulfide with naproxen, a non-steroidal, anti-inflammatory drug. ATB-352 is an H2S-releasing derivative of ketoprofen, a potent NSAID commonly prescribed for acute pain. Its IBD candidates are being designed to maintain the efficacy, safety, and pharmacokinetic properties of ATB-429.


GREY:ATBPF - Post by User

Post by cpacon Feb 11, 2020 9:13am
184 Views
Post# 30672937

Let's be clear about DEAL/Partnership:

Let's be clear about DEAL/Partnership:Magicbox and a couple others getting their panties in a twist about the talk around a deal on our lead drug. A few points to consider:
1) Management has always said they intended to partner after phase II.  All I said is that they are likely talking to big pharma now and I maintain that.  If you want a partnership, you don't wait until the day after you publish results to start those conversations.  It can be a long process, so you should be generating interest well before results are published.  
2) Trust me, big pharma needs small innovators biopharmas just as much as the other way around.  I have had the privilege to speak with mgmt of Merck, Pfizer and BMY over the years and their number 1 concern is usually 'the patent cliff' ... usually half their pipelines are in-licensed.  They just don't generate enough internally to offset maturing drugs.  
3)  Partnerships can and do happen at any time in the process.  Take a look at Turnstone Biologics which entered into a BILLION dollar deal with Takeda, even though the drug was preclinical.  Takeda partnered with them for the platform.  And yes, we also have a drug platform that applies not only to our lead drug, but potentially a whole portfolio behind that.

Cheers,
Cpac.

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